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11-/05/04 12:37 FAX 856 810 1454 



LICATA & TYRRELL 



PTOBF 



@)001 



FACSIMILE COVER SHE 
Licata & Tyrrell P.C. 

66 E. Main Street 
Marlton, New Jersey 

Tel: (856) 810-1515 
Fax: (856) 810-1454 
E-Mail: JMLicata@licataandtyrrell.coni 

November 5, 2004 



GROUP: 1635 

FAX NUMBER: 1-703^872-9306 
ATTORNEY DOCKET NO,: RTSP-0155 
SERIAL NO.: 09/913,800 
FILED: March 1,2002 
CUSTOMER NO.: 32862 
CONFIRMATION NO,: 4042 

NUMBER OF PAGES: 10 

(including this sheet) 

MESSAGE: Attached is an Amendment Transmittal Letter (in duplicate) and a 
Reply to Restriction Requirement and Preliminary Amendment 
in response to Restriction Requirement dated October 6, 2004. 



URGENT! PLEASE DELIVER IMMEDIATELY UPON RECEIPT. THANK YOU! 

If you have any questions, or did not receive the proper number of pages, or had trouble 
during transmission, please call 856-810-1515. 

CONFIDENTIALITY NOTICE 

The information contained in ibis facsimile message uj legally privileged and confidential, and intended only for the uac of the mdividuiilfe) and/ox coutyCies) 
named *bov* . tf you are not the intended recipient, you arc hereby nedfiod thai any unauthorized disclosure, copvirtfl dlwiburion or taking of any action in 
reliance on ihe tunrents of the telecopied materials is slrialy prphioiwd and review by any individual other Than the intended recipient shall not constitute 
waiver of the anoraey client privilege. If you have received this transmission in error, please immediately notify us by telephone in order to arrange lor the 

reuirn of tl>e inalcrials. Thank you. 



E T 



RECEIVED 
CENTRAL FAX CENTER 

NOV 0 5 2004 



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LICATA & TYRRELL 



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@002 



AMENDMENT TRANSMITTAL LETTER (Large Entity) 
Applicant(s): MoDia and Cowsert 



Application No. 
09/913,800 



Filing Date 
March 1, 2002 



Examiner 
James Schultz 



Customer No, 
32862 



Docket No. 
KTSP-0155 



Group Art Unit 
1635 



Confirmation No. 
4042 



Invention; ANTISENSE MODULATION OF AKT-2 EXPRESSION 



COMMISSIONER FOR PATENTS; 

Transmitted herewith is an amendment in the above-identified application. 
The fee has been calculated and is transmitted as shown below. 



CLAIMS AS AMENDED 



TOTAL CLAIMS 



INDEP. CLAIMS 



CLAIMS REMAINING 
AFTER AMENDMENT 



16 



HIGHEST # 
PREV. PAID FOR 



20 



NUMBER EXTRA 
CLAIMS PRESENT 



RATE 



$18.00 



$86.00 



Multiple Dependent Claims (check if applicable) 



TOTAL ADDITIONAL FEE FOR THIS AMENDMENT 



ADDITIONAL 

FEE 



$0,00 



$0.00 



$0.00 



$0.00 



SI No additional fee is required for amendment 

□ Please charge Deposit Account No. in the amount of 

□ A check in the amount of to cover the filing fee is enclosed. 

IS The Director is hereby authorized to charge payment of the following fees associated with this 
communication or credit any overpayment to Deposit Account 50-1619 
53 Any additional fifing fees required under 37 C.F.R. 1.16. 
IS Any patent application processing fees under 37 CFR 1.17. 

□ Payment by credit card. Form PTO-2038. 

WARNING: Information on this form may become public. Credit card information should not be 
included on this form. Provide credit card information and authorization on PTO-2038. 



Dated: November 5* 2004 



Signature 



Jane Massey Licata 
Reg. No. 32,257 
Licata & TyrreU P.C. 
66 E. Main Street 
Marlt<ro,NJ 08053 
Tell 856-810-1515 
Fax: 856-810-1454 



cc: 



I hereby certify that this correspondence is being deposited with 
the United States Postal Service with sufficient postage as first 
dass mall in an envelope addressed to ■CcmmfssionBr for Patents, 
P.O. Box 1450, Alexandria, VA2231^-145£T 137 CFR 1.8(a)] on 



(Dete) 



Signature of Person Mailing Cerrespvndence 



Typed or Printed Name of Person Mailing Correspondence 



phi APftp/REVoa 



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LICATA & TYRRELL 



PTOBF 



©003 



AMENDMENT TRANSMITTAL LETTER (Lajrge Entity) 
Appltcant(s): Monia and Cowsert 


Docket No. 
RTSP-0155 


AppNcation No. 
09/913,800 


Filing Date 
March 1,2002 


Examiner 

James Scbultz 


Customer No. 
32862 


Group Art Unit 
1635 


Confirmation No. 

4042 



Invention: ANTTSENSE MODULATION OF AKT-2 EXPRESSION 



COMMISSIONER FOR PATENTS: 

Transmitted herewith is an amendment in the above-identified application. 
The fee has been calculated and Is transmitted as shown below. 



CLAIMS AS AMENDED 





CLAIMS REMAINING 
AFTER AMENDMENT 


HIGHEST # 
PREV. PAID FOR . 


NUMBER EXTRA 
CLAIMS PRESENT 


RATE 


ADDITIONAL 
FEE 


TOTAL CLAIMS 


16 


20 


0 


X $18.00 


$0.00 


INDEP. CLAIMS 


1 


3 


0 


x 586,00 


$0.00 


Multiple Dependent Claims (check if applicable) 


□ 






$0.00 


TOTAL ADDITIONAL FEE FOR THIS AMENDMENT 


$0.00 



SI No additional fee is required for amendment. 

□ . Please charge Deposit Account No. in the amount of 

□ A check in the amount of to cover the filing fee is enclosed. 

K) The Director is hereby authorized to charge payment of the following fees associated with this 
communication or credit any overpayment to Deposit Account 50-1619 
IS Any additional filing fees required under 37 C.F.R. 1.16. 
IS Any patent application processing fees under 37 CFR 1 .17. 

□ Payment by credit card. Form PTO-2038. 

WARNING: Information on this form may become public. Credit card information should not be 
included on this form. Provide credit card information and authorization on PTO-2038. 



Dated; November 5, 2004 



Signature 



Jane Massey Licata 
Reg. No. 32*257 
Licata & Tyrrell P.C. 
66 E. Main Street 
Marlton f NJ 08053 
Tel: 856-810-1515 
Fax: 856-810-1454 



cc; 



I hereby certify that this correspondence is being deposited with 
the United States Postal Service with sufficient postage* as first 
class mail In an envelope addressed to "Commissioner for Patents, 
P.O. Box 1450, Alexandria, VA 22313-1450" [37 CFR 1.8(a)] on 



(Dnta) 



Signature of Person Mailing Correspondence 



Typed or Printed Name of Person Mailing Correspondence 



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LICATA & TYRRELL 



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CERTIFICATE OF TRANSMISSION BY FACSIMILE (37 CFR 1.8) 

Applicant(s): Monia and Cowsert 



Docket No. 
RTSP-0155 



Application No. 
09/913,800 



Filing Date . 
March 1, 2002 



Examiner 
James Schultz 



Group Art Unit 
1635 



Invention; ANTISENSE MODULATION OF AKT-2 EXPRESSION 



I hereby certify that this Iteply to Restriction Requirement and Preliminary Amendment 

(Identify type of correspondence) 

is being facsimile transmitted to the United States Patent and Trademark Office (Fax. No. 703-872-9306 ) 
on November 5,2004 



(Date) 



Jane Massey Licata 



(Typed or Printed Nam* of Person Signing Certificate) 
0 (Signature) 



Note: Each paper must have its own certificate of mailing. 



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LICATA & TYRRELL 



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IN THE UNITED STATES PATENT AND TRADEMARK OFFICE 



Attorney Docket No. : 



RTSP-0155 



Inventors : 



Monia and Cowsert 



RECEIVED 
CENTRAL FAX CENTER 



Serial No. : 



09/913,800 



NOV 0 5 20M 



Filing Date : 



March 1, 2002 



Examiner : 



Schulfcz , James 



Customer No 



32862 



Group Art Unit: 



1635 



Confirmation No.: 



4042 



Title: 



Antisense Modulation of AKT-2 Expression 



Certificate of Facsimile Transmission 

I hereby certify that this paper is being facsimile 
transmitted to the Patent and Trademark Office on 
the date shown below. 

On November 5. 2004 



Jane Massey Licata Registration No. 32,257 

Commissioner for Patents 
Washington, DC 20231 

Dear Sir: 

REPLY TO RESTRICTION REQUIRMENT AND PRELIMINARY AMENDMENT 

This letter is a reply to the Restriction Requirement mailed 
October 6, 2004 setting a one (1) month period for response- 
Please enter the following remarks into the record- 
Amendments to the Claims are reflected in the listing of 
claims which begin on page 2 of this paper. 
Remarks being on page 5 of this paper. 



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